School of Graduate Studies

MD-PhD Program

joshua schwartzenburg

Name: Joshua Schwartzenburg

Year in Program: Sixth year (fourth in grad school)

Department: Biochemistry and Molecular Biology

Mentor: Dr. Shyamal Desai

Hometown: Baton Rouge, LA

Education: Undergraduate - Louisiana State University in Baton Rouge

Past Research Experience:

Dr. James Moroney's Lab, Department of Biological Sciences at LSU, Project: Characterization of a putative CCM transporter, CIA8, in Chlamydomonas reinhardtii using RNAi knockdown mutants

Publications:

Schwartzenburg J, Reed R, Koul H, Zea A, Shellito J, Miele L, Crabtree J, Desai S (2022) ISGylation is increased in the peripheral blood mononuclear cells derived from symptomatic

COVID-19 patients. Experimental Biology and Medicine. X(X): 1-6 [PMID:35130743] Mirzalieva O, Juncker M, Schwartzenburg J, Desai S (2022) ISG15 and ISGylation in human diseases. Cells. 11(3): 538 [PMID:35159348]

Juncker M, Kim C, Reed R, Haas A, Schwartzenburg J, and Desai S (2021) ISG15 attenuates post-translational modifications of mitofusins and congression of damaged mitochondria in ataxia telangiectasia cells. BBA Molecular Basis of Disease. 1867 (6): 1-14 [PMID:33617986]

Kim C, Juncker M, Reed R, Haas A, Guidry J, Matunis M, Yang WC, Schwartzenburg J, and Desai S (2021) SUMOylation of mitofusins: a potential mechanism for perinuclear mitochondrial congression in cells treated with mitochondrial stressors. BBA Molecular Basis of Disease. 1867(6): 1-15 [PMID:33617988]

Schwartzenburg J, Juncker M, Reed R, and Desai S (2018) Increased ISGylation in cases of TBI-exposed ALS veterans. Journal of Neuropathology & Experimental Neurology. 78(3):209–218 [PMID:30657969]

Machingura MC, Bajsa-Hirschel J, Laborde SM, Schwartzenburg JB, Mukherjee B, Mukherjee A, Pollock SV, Förster B, Price GD, and Moroney JV (2017) Identification and characterization of a solute carrier, CIA8, involved in inorganic carbon acclimation in Chlamydomonas reinhardtii. Journal of Experimental Botany. 68(14): 3879–3890 [PMID:28633328]

Current Research Interest:  Exploring the role of the ubiquitin-like protein, ISG15, in traumatic brain injury (TBI), alcohol use, and neurodegenerative disease in rats

Current Medical Interest:Traumatic brain injury, Neurodegeneration, Pathology

Career Goal: To become a pathologist

What makes you unique? I'm a member of the Tangirnaq Native Village, a federally recognized Native Alaskan Tribe